Category Archives: Organic Chemistry

Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, composition, reactions, and preparation (by synthesis or by other means) of carbon-based compounds, hydrocarbons, and their derivatives. These compounds may contain any number of other elements, including hydrogen, nitrogen, oxygen, the halogens as well as phosphorus, silicon, and sulfur.

Molecule of the Month (March) – Ibuprofen

From Wikipedia:

Ibuprofen (INN); from the nomenclature iso-butyl-propanoic-phenolic acid) is a nonsteroidal anti-inflammatory drug (NSAID) used for relief of symptoms of arthritis, fever, as an analgesic (pain reliever), especially where there is an inflammatory component, and dysmenorrhea.

Ibuprofen is known to have an antiplatelet effect, though it is relatively mild and somewhat short-lived when compared with aspirin or other better-known antiplatelet drugs. In general, ibuprofen also acts as a vasodilator, having been shown to dilate coronary arteries and some other blood vessels. Ibuprofen is a core medicine in the World Health Organization‘s “WHO Model List of Essential Medicines“, which is a list of minimum medical needs for a basic healthcare system.

Ibuprofen was derived from propionic acid by the research arm of Boots Group during the 1960s. It was discovered by Andrew RM Dunlop, with colleagues Stewart Adams, John Nicholson, Vonleigh Simmons, Jeff Wilson and Colin Burrows, and was patented in 1961. Originally marketed as Brufen, ibuprofen is available under a variety of popular trademarks, including Motrin, Nurofen, Advil, and Nuprin.

Chemical Structure of Ibuprofen

Athletes, the young, the old, the sick alike all use Ibuprofen. Can you recall the last time you were prescribed this chemical? Take care though… from personal experience, this drug, as well as most drugs… cause gastric discomfort 😦

Ibuprofen Tablets

Links:
http://en.wikipedia.org/wiki/Ibuprofen
http://www.chem.ox.ac.uk/mom/ibuprofen/ibuprofen.html

Maxim

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Filed under General, Organic Chemistry